Sometimes a large or painful pimple or acne cyst may erupt causing significant discomfort. This type of breakout may require more immediate treatment than topical creams or oral medications can provide. In these cases, the use of medicated injections containing cortisone is very helpful. The result of this type of acne treatment is usually very fast, causing the acne breakout to shrink and melt away quickly. While this treatment is very helpful for isolated acne breakouts, it does not prevent future breakouts and is not useful as a comprehensive acne treatment.